Prof. Dr. Vahide SAVCI - UÜTF Tıbbi Farmakoloji Anabilim Dalı

Akademik Kadro - Prof. Dr. Vahide SAVCI

Pozisyonu

Prof. Dr. Vahide SAVCIProfesör
Uludağ Üniversitesi Tıp Fakültesi
Farmakoloji ve Klinik Farmakoloji Anabilim Dalı
Görükle Kampüsü, Bursa, 16059


Tel : +90 (224) 295 3551
Faks : +90 (224) 442 81 02
Email: vsavci@uludag.edu.tr

 

İLGİLENDİĞİ ARAŞTIRMA ALANLARI

  • Kolinerjik Nörofarmakoloji
  • Kardiyovasküler Düzenleme
  • İskemi ve Kardiyovasküler Şok Farmakolojisi
  • Nöroendokrin Düzenleme

 

Üyelİklerİ

  • Türk Farmakoloji Derneği
  • Society for Neuroscience (U.S.A.)
  • Türk Tabipleri Birliği

 

YABANCI DİL

  • İngilizce

 

ÖDÜLLERİ

  • (1997-1998) NOVARTIS Farmakoloji Dalı Araştırma Ödülü Birincilik Ödülü
  • (2002-2003) NOVARTIS Farmakoloji Dalı Araştırma Ödülü Birincilik Ödülü

 

BAŞLICA YAYINLARI

  1. Arslan B.Y., Ulus I.H., Savci V., Kiran B.K. (1991) Effects of intracerebroventricular injected choline on cardiovascular functions and sympathoadrenal activity. J. Cardiovascular Pharmacol., 17 (5), 814-821.
  2. Savci V. and Wurtman R.J. (1995) Effects of cytidine on membrane phospholipid synthesis in rat striatal slices. J. Neurochem., 64 (1), 378-384 .
  3. Lopez-Coviella I., Agut J., Savci V., Ortiz A.J., Wurtman R.J.(1995) Evidence that 5'-cytidinediphospho- choline can affect brain phospholipid composition by increasing choline and cytidine plasma levels. J. Neurochem., 65 (2):889-894.
  4. Ulus I.H., Arslan B.Y., Savci V., Kiran B.K.(1995) Restoration of blood pressure by choline treatment in rats made hypotensive by haemorrhage. Br. J. Pharmacol., 116 (2), 1911-1917.
  5. Savci V., Gurun M.S., Ulus I.H., Kiran B.K. (1996) Intracerebroventricular injection of choline increases plasma oxytocin levels in conscious rats. Brain Res., 709 (1), 97-102.
  6. Farber S.A., Savci V., Wei A., Slack B.E., Wurtman R.J. (1996) Choline's phosphorylation in rat striatal slices is regulated by the activity of cholinergic neurons. Brain Res., 723 (1-2), 90-99.
  7. Savci V., Gurun M.S., Ulus I.H., Kiran B.K. (1996) Effect of intracerebroventricularly injected choline on plasma ACTH and ?-endorphine levels in conscious rats. Eur. J. Pharmacol., 309 (3), 275-280.
  8. Savci V. and Ulus I.H. (1996) Central choline reverses hypotension caused by alpha-adrenoceptor or ganglion blockade in rats: the role of vasopressin. Eur. J. Pharmacol., 311(2-3), 153-161.
  9. Gurun M. S., SavciV. and Ulus I.H. (1997) Intracerebroventricular choline reverses hypotension induced by acute chemical sympathectomy. J. Auto. Pharmacol. 17 (3), 155-163.
  10. Gurun M.S., SavciV., Ulus I.H. and Kiran B.K. (1997) Centrally administrated choline increases plasma prolactin levels in conscious rats. Neurosci. Lett. 232 (2), 79-82.
  11. Savci V. and Ulus I.H. (1997) Cardiovascular effects of central choline during endotoxin shock in the rat. J. Cardiovasc. Pharmacol., 30 (5), 667-675.
  12. Savcı V. and Ulus İ.H. (1998) Choline administration reverses hypotension in spinal cord transected rats: The involvement of vasopressin. Neurochem. Res. 23 (5), 733-741.
  13. Yavascaoglu I., Savci V., Oktay B., Simsek U., Ozyurt M. (1998) The effects of ejaculation on serum prostate-specific antigen (PSA). Int. Urol. Nephrol. 30 (1), 53-58.
  14. Savci V., Gurun M.S., Cavun S. and Ulus I.H. (1998) Cardiovascular effects of centrally injected tetrahydroaminoacridine in conscious normotensive rats. Eur J. Pharmacol. 346 (19), 35-41.
  15. Savci V., Cavun S., Gurun M.S. and Ulus I.H. (2001) Reversal of haemorrhagic shock in rats by tetrahydroaminoacridine. Pharmacology. 62(1), 36-44.
  16. Savci V., Cavun S., Goktalay G., Ulus I.H. (2002) Cardiovascular effects of intracerebroventricularly injected CDP-choline in normotensive and hypotensive rats: the involvement of cholinergic system. Naunyn Schm Arch Pharmacol. 365 (5) : 388 - 398.
  17. Savci V, Goktalay G, Ulus I.H. (2002) Intracerebroventricular choline increases plasma vasopressin and augments plasma vazopressin response to osmotic stimulation and hemorrhage. Brain Res. 948 ( 1 - 2 ) : 58 - 70.
  18. Savci V., Goktalay G., Cansev M., Cavun S., Yilmaz M.S.Ulus I.H. (2003). Intravenously injected CDP-choline increases blood pressure and reverses hypotension in haemorrhagic shock : effect is mediated by central cholinergic activation, Europan Journal of Pharmacology, 468:129-139.
  19. Cavun S., Savci V., Ulus I.H. (2004).Centrally injected CDP-choline increases plasma vasopressin levels by central cholinergic activation. Fundamental & Clinical Pharmacology 18: 71-77.
  20. Yalcin M., Savci V. (2004) Restoration of Blood Pressure by Centrally Injected U-46619, a Thromboxane A2 Analog, in Hemorrhaged Hypotensive Rats: Investigation of Different Brain Areas, Pharmacology 70:177-187.
  21. Cavun S and Savci V (2004) CDP-choline increases plasma ACTH and potentiates the stimulated release of GH, TSH and LH: the cholinergic involvement. Fundam. Clin. Pharmacol.18, 513-523.
  22. Erturk E., Kuru N., Savci V., Tuncel E., Ersoy C., Imamoglu S. (2004) Serum leptin levels correlate with obesity parameters but not with hyperinsulinism in women with polycystic ovary syndrome, Fertility and Sterility, 82 (5), 1364-1368.
  23. Yalcin M., Cavun S., Yilmaz MS and Savci V. (2005) The involvement of central cholinergic system in the pressor effect of intracerebroventricularly injected U-46619, a thromboxane A2 analog, in conscious normotensive rats. Naunyn-Schmiedeberg's Arch Pharmacol 372; 31-40.
  24. Yalcin M., Cavun S., Yilmaz MS., Cengiz F. and Savci V. (2005) The involvement of brain thromboxane A2 in hypotension induced by haemorrhage in rats. Clin Exp Pharmacol Physiol 32.
  25. Yilmaz MS., Yalcin M. and Savci V. (2006) Cytidine 5'-diphosphocholine restores blood flow of superior mesenteric and renal arteries and prolongs survival time in haemorrhaged anaesthetized rats. Clin Exp Pharmacol Physiol. 33(5-6):415-20.
  26. Gullulu M, Akdag I, Kahvecioglu S, Filiz G, Savci V. (in press) Aldosterone blockage in proliferative glomerulonephritis prevents not only fibrosis, but proliferation as well. Ren Fail. 28: 509-14.
  27. Yalcin M., Cavun S., Yilmaz MS.,and Savci V. (in press) Activation of the central cholinergic system mediates the reversal of hypotension by centrally administrated U-46619, a thromboxane A2 analog, in hemorrhaged rats. Brain Res.
  28. Karaalp A, Akıcı A, Gören MZ, Erdivanlı B, Savcı V, Ulus IH, Oktay Ş. (In press) Hemorragic shock in doca-salt hypertensive rats: Effects of oxotremorine on blood pressure and vasopressin release. Pharmacologyonline. 2: 109-127.

 

KİTAP BÖLÜMLERİ

  • Vahide Savcı (2004) Gastorintestinal Hormonlar, Klinik Gastroenteroloji, Editör: Prof. Dr. Faruk Memik, Nobel Tıp Kitabevleri Ltd. Şti, İstanbul, Türkiye, 1. baskı, 299-320.
  • Vahide Savcı (2006) Antidepresan ilaçların farmakolojik özellikleri. Türkiye Klinikleri, 2(1),22-31.