Prof. Dr. Sinan ÇAVUN - UÜTF Tıbbi Farmakoloji Anabilim Dalı

Akademik Kadro - Prof. Dr. Sinan ÇAVUN

Pozisyonu

Doç. Dr. Sinan ÇAVUNDoçent
Uludağ Üniversitesi Tıp Fakültesi
Farmakoloji ve Klinik Farmakoloji Anabilim Dalı
Görükle Kampüsü, Bursa, 16059


Tel : +90 (224) 295 3565
Faks : +90 (224) 442 81 02
Email: scavun@uludag.edu.tr

 

İLGİLENDİĞİ ARAŞTIRMA ALANLARI

  • Kardiyovasküler Sistemin Nöral Kontrolü
  • Opioiderjik Nörofarmakoloji
  • Nöroendokrin Düzenleme

Üyelİklerİ

  • Türk Farmakoloji Derneği
  • Türk Tabipleri Birliği

 

YABANCI DİL

  • İngilizce

ÖDÜLLERİ, BURSLARI

  • (1997) XIV. Ulusal Farmakoloji Kongresi
    Mansiyon
  • (2002-2003) NOVARTIS Farmakoloji Dalı Araştırma Ödülü
    Birincilik ödülü
  • (2003) International Narcotics Research Conference (INRC), Perpignan, France
    Seyahat bursu

BAŞLICA YAYINLARI

  1. Savci V., Gürün M.S., Çavun S. and Ulus I.H. (1998) Cardiovascular effects of centrally injected tetrahydroaminoacridine in conscious normotensive rats. Eur. J. Pharmacol. 3; 346(1): 35-41.
  2. Savci V., Çavun S., Gürün M.S. and Ulus I.H. (2001) Reversal of haemorrhagic shock in rats by tetrahydroaminoacridine. Pharmacol. 62: 36-44.
  3. Cavun S., Resch G.E., Evec A.E., Rapacon-Baker M.M. and Millington W.R. (2001) Blockade of delta opioid receptors in the ventrolateral periaqueductal gray region inhibits the fall in arterial pressure evoked by hemorrhage. JPET 297:612-619.
  4. Cavun S. and Millington W.R. (2001) Evidence that hemorrhagic hypotension is mediated by the ventrolateral periaqueductal gray region. Am. J. Physiol. Reg. Integ. Comp. Physiol. 281: R747-R752.
  5. Savci V., Cavun S., Goktalay G. and Ulus I.H. (2002) Cardiovascular effect of intracerebroventricularly injected CDP-choline in normotensive and hypotensive animals: the involvement of cholinergic system. Naunyn-Schmiedeberg's Arch Pharmacol. 365 (5): 388-398.
  6. Savci V., Goktalay G., Cansev M., Cavun S., Yilmaz M.S.Ulus I.H. (2003). Intravenously injected CDP-choline increases blood pressure and reverses hypotension in haemorrhagic shock : effect is mediated by central cholinergic activation, Europan Journal of Pharmacology, 468:129-139.
  7. Cavun S., Savci V., Ulus I.H. (2004) Centrally injected CDP-Choline increases plasma vasopressin levels by central cholinergic activation. Fund. and Clin. Pharm. 18: 71-77.
  8. Cavun S, Goktalay G, Millington WR. (2004) The hypotension evoked by visceral nociception is mediated by delta opioid receptors in the periaqueductal gray. Brain Res. 1019(1-2):237-45.
  9. Cavun S, Savci V.(2004) CDP-choline increases plasma ACTH and potentiates the stimulated release of GH, TSH and LH: the cholinergic involvement. Fundam Clin Pharmacol. 18(5): 513-23.
  10. Cavun S, Goktalay G, Millington WR. (2005) Glycyl-glutamine, an endogenous beta-endorphin-derived peptide, inhibits morphine-induced conditioned place preference, tolerance, dependence, and withdrawal. J Pharmacol Exp Ther. 315(2):949-58.
  11. Yalcin M, Cavun S, Yilmaz MS, Savci V. (2005) The involvement of central cholinergic system in the pressor effect of intracerebroventricularly injected U-46619, a thromboxane A2 analog, in conscious normotensive rats. Naunyn Schmiedebergs Arch Pharmacol. 372(1):31-40.
  12. Yalcin M, Cavun S, Yilmaz MS, Cengiz F, Savci V. (2005) Involvement of brain thromboxane A in hypotension induced by haemorrhage in rats. Clin Exp Pharmacol Physiol. 32(11):960-67.
  13. Goktalay G, Cavun S, Levendusky MC, Hamilton JR, Millington WR. (2006) Glycyl-glutamine inhibits nicotine conditioned place preference and withdrawal. Eur J Pharmacol. 530(1-2):95-102.
  14. Goktalay G, Cavun S, Levendusky MC, Resch GE, Veno PA, Millington WR. (2006) Hemorrhage activates proopiomelanocortin neurons in the rat hypothalamus. Brain Res. 1070(1):45-55.
  15. Yalcin M., Cavun S., Yilmaz MS.,and Savci V. (in press) Activation of the central cholinergic system mediates the reversal of hypotension by centrally administrated U-46619, a thromboxane A2 analog, in hemorrhaged rats. Brain Res.